Neurology

 

Reference Library

• Publications & Guidelines Known to Use KetoCal

  References Available:

  • 1. Hallböök T, Kohler S, Rosen I, et al. Effects of ketogenic diet on epileptiform activity in children with therapy resistant epilepsy. Epilepsy Res. 2007;77(2-3):134-40. PubMed
  • 2. Rubenstein JE. Use of the ketogenic diet in neonates and infants. Epilepsia. 2008;49(s8):30-2. PubMed
  • 3. Kossoff EH, Hedderick EF, Turner Z, et al. A case-control evaluation of the ketogenic diet versus ACTH for new-onset infantile spasms. Epilepsia. 2008;49(9):1504-9. PubMed
  • 4. Hong AM, Turner Z, Hamdy RF, et al. Infantile spasms treated with the ketogenic diet: Prospective single-centerexperience in 104 consecutive infants. Epilepsia. 2010;51(8):1403-7. PubMed
  • 5. Nabbout R, Mazzuca M, Hubert P, et al. Efficacy of ketogenic diet in severe refractory status epilepticus initiating fever induced refractory epileptic encephalopathy in school age children(FIRES). Epilepsia. 2010;51(10):2033-7. PubMed
  • 6. Coppola G, Verrotti A, Ammendola E, et al. Ketogenic diet for the treatment of catastrophic epileptic encephalopathies in childhood. Eur J Paediatr Neurol. 2010;14(3):229-34. PubMed
  • 7. Wusthoff CJ, Kranick SM, Morley JF, et al. The ketogenic diet in treatment of two adults with prolonged nonconvulsive status epilepticus. Epilepsia. 2010;51(6):1083-5. PubMed
  • 8. Urbizu A, Cuenca-Leon E, Raspall-Chaure M, et al. Paroxysmal exercise-induced dyskinesia, writer's cramp, migraine with aura and absence epilepsy in twin brothers with a novel SLC2A1 missense mutation. J Neurol Sci. 2010;295:110-3. PedMed
  • 9. Zupec-Kania B. Enteral and Parenteral Applications of Ketogenic Diet Therapy: Experiences From Four Centers. ICAN: Infant, Child, & Adolescent Nutrition. 2011;3:274-81. PubMed
  • 10. Cervenka MC, Hartman AL, Venkatesan A, et al. The ketogenic diet for medically and surgically refractory status epilepticus in the neurocritical care unit. Neurocrit Care. 2011;15(3):519-24. PubMed
  • 11. Roan M. Management of Long-Term Ketogenic Parenteral Nutrition. ICAN: Infant, Child, & Adolescent Nutrition. 2011;3:282-7. Sagepub
  • 12. Kossoff EH, Dorward JL, Turner Z, et al. Prospective study of the modified atkins diet in combination with a ketogenic liquid supplement during the initial month. J Child Neurol. 2011;26(2):147-51. PubMed
  • 13. Christodoulides SS, Neal EG, Fitzsimmons G, et al. The effect of the classical and medium chain triglyceride ketogenic diet on vitamin and mineral levels. J Hum Nutr Diet. 2012;25(1):16-26. PubMed
  • 14. Cusmai. Ketogenic diet in early myoclonic encephalopathy due to non ketotic hyperglycinemia. Eur J Paediatr Neurol. 2012;16:509-13. PubMed
  • 15. Suo C, Liao J, Lu X, et al. Efficacy and safety of the ketogenic diet in Chinese children. Seizure. 2013;22(3):174-8. PubMed
  • 16. El-Rashidy OF. Modified Atkins diet vs classic ketogenic formula in intractable epilepsy. Acta Neurol Scand. 2013;128(6):402-8. PubMed
  • 17. Sort R, Born AP, Pedersen KN, et al. Ketogenic diet in 3 cases of childhood refractory status epilepticus. Eur J Paediatr Neurol. 2013;17(6):531-6. PubMed
  • 18. Kossoff EH, Henry BJ, Cervenka MC. Efficacy of dietary therapy for juvenile myoclonic epilepsy. Epilepsy Behav. 2013;26(2):162-4. PubMed
  • 19. Strzelczyk A, Reif PS, Bauer S, et al. Intravenous initiation and maintenance of ketogenic diet: proof of concept in super-refractory status epilepticus. Seizure. 2013;22(7):581-3. PubMed
  • 20. Pires M. Ketogenic diet for infantile spasms refractory to first-line treatments: An open prospective study. Epilepsy Research. 2013;13:S0920-1211. PubMed
  • 21. Caraballo RH, Flesler S, Armeno M, et al. Ketogenic diet in pediatric patients with refractory focal status epilepticus. Epilepsy Res. 2014;108(10):1912-6. PubMed
  • 22. Groveman SA. Ketogenic Diet Patients' Lipid Profiles Improved with KetoCal 4:1 Liquid: A Case Series. ICAN Infant Child Adolesc Nutr. 2015;7(3):157-161. Sagepub
  • 23. Dressler A, Trimmel-Schwahofer P, Reithofer E, et al. Efficacy and tolerability of the ketogenic diet in Dravet syndrome - Comparison with various standard antiepileptic drug regimen. Epilepsy Res. 2015; 109:81-9. PubMed
  • 24. Dressler A, Trimmel-Schwahofer P, Reithofer E, et al. The ketogenic diet in infants - Advantages of early use. Epilepsy Res. 2015; 116:53-8. PubMed
  • 25. van der Louw E, van den Hurk D, Neal E, et al. Ketogenic diet guidelines for infants with refractory epilepsy. Eur J Paediatr Neurol. 2016. PubMed
  • 26. Ashrafi MR, Hosseini SA, Zamani GR, et al. The efficacy of the ketogenic diet in infants and young children with refractory epilepsies using a formula-based powder. Acta Neurol Belg. 2017; 117:175-82. PubMed
  • 27. Sampaio LPB, Takakura C, Manreza MLG. The use of a formula-based ketogenic diet in children with refractory epilepsy. Arq Neuropsiquiatr. 2017; 75:234-7. PubMed
  • 28. Weijenberg A, van Rijn M, Callenbach PMC, et al. Ketogenic Diet in Refractory Childhood Epilepsy: Starting with a Liquid Formulation in an Outpatient Setting. Child Neurol Open. 2018; 5:2329048. PubMed
  • 29. McDonald TJW, Henry-Barron BJ, Felton EA, et al. Improving compliance in adults with epilepsy on a modified Atkins diet: A randomized trial. Seizure. 2018; 60:132-8. PubMed
  • 30. Karimzadeh P, Moosavian T, Moosavian HR. Effects of a Formula-Based Ketogenic Diet on Refractory Epilepsy in 1 to 3 Year-Old Patients under Classic Ketogenic Diet. Iran J Child Neurol. 2019;13:83-90. PubMed
• The Ketogenic Diet for Children with Intractable Epilepsy

  Clinical References for The Ketogenic Diet for Children with Intractable Epilepsy.

  • Aguirre Castaneda RL, et al. Successful treatment of type 1 diabetes and seizures with combined ketogenic diet and insulin. Pediatrics. 2012 Feb;129(2):e511-4. PubMed
  • Cusmai R, et al. Ketogenic diet in early myoclonic encephalopathy due to non ketotic hyperglycinemia. Eur J Paediatr Neurol. 2012 Jan 17. [Epub ahead of print] PubMed
  • Groomes LB, et al. Do patients with absence epilepsy respond to ketogenic diets? J Child Neurol. 2011 Feb;26(2):160-5. PubMed
  • Dressler A, et al. Long-term outcome and tolerability of the ketogenic diet in drug-resistant childhood epilepsy--the Austrian experience. Seizure. 2010 Sep;19(7):404-8. PubMed
  • Patel A, et al. Long-term outcomes of children treated with the ketogenic diet in the past. Epilepsia. 2010 Jul;51(7):1277-82. PubMed
  • Kossoff EH. The ketogenic diet: an appropriate first-line therapy? Expert Rev Neurother. 2010 Jun;10(6):843-5. PubMed
  • Coppola G, et al. Ketogenic diet for the treatment of catastrophic epileptic encephalopathies in childhood. Eur J Paediatr Neurol. 2010 May;14(3):229-34. PubMed
  • Kossoff EH, et al. Ketogenic Diets: An Update for Child Neurologists. J Child Neurol. 2009 Aug;24(8):979-88. PubMed
  • Neal EG, et al. A randomized trial of classical and medium-chain triglyceride ketogenic diets in the treatment of childhood epilepsy. Epilepsia. 2009;50(5):1109–17. PubMed
  • Rubenstein JE. Use of the ketogenic diet in neonates and infants. Epilepsia. 2008 Nov;49 Suppl 8:30-2. PubMed
  • Kossoff EH, et al. Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study Group. Epilepsia. 2009 Feb;50(2):304-17. PubMed
  • Freeman JM, et al. The ketogenic diet: one decade later. Pediatrics. 2007 Mar;119(3):535-43. Abstract
  • Bergqvist AG, et al. Vitamin D status in children with intractable epilepsy, and impact of the ketogenic diet. Epilepsia. 2007 Jan;48(1):66-71. PubMed
  • Hartman AL, et al. Clinical aspects of the ketogenic diet. Epilepsia. 2007 Jan;48(1):31-42. Abstract
  • Bough KJ, et al. Anticonvulsant mechanisms of the ketogenic diet. Epilepsia. 2007 Jan;48(1):43-58. PubMed
  • Groesbeck DK, et al. Long-term use of the ketogenic diet in the treatment of epilepsy. Dev Med Child Neurol. 2006 Dec;48(12):978-81. PubMed
  • Henderson CB, et al. Efficacy of the ketogenic diet as a treatment option for epilepsy: meta-analysis. J Child Neurol. 2006 Mar;21(3):193-8. PubMed
  • Bergqvist AG, et al. Fasting versus gradual initiation of the ketogenic diet: a prospective, randomized clinical trial of efficacy. Epilepsia. 2005 Nov;46(11):1810-9. PubMed
  • Rubenstein JE, et al. Experience in the use of the ketogenic diet as early therapy. J Child Neurol. 2005 Jan;20(1):31-4. PubMed
  • Pfeifer HH, et al. Low-glycemic-index treatment: a liberalized ketogenic diet for treatment of intractable epilepsy. Neurology. 2005 Dec 13;65(11):1810-2. PubMed
  • Kossoff EH, et al. Benefits of an all-liquid ketogenic diet. Epilepsia. 2004 Sep;45(9):1163. PubMed
  • Mandel A, et al. Medical costs are reduced when children with intractable epilepsy are successfully treated with the ketogenic diet. J Am Diet Assoc. 2002 Mar;102(3):396-8. PubMed
  • Hemingway C, et al. The ketogenic diet: a 3- to 6-year follow-up of 150 children enrolled prospectively. Pediatrics. 2001 Oct;108(4):898-905. PubMed
  • Freeman JM, et al. The efficacy of the ketogenic diet-1998: a prospective evaluation of intervention in 150 children. Pediatrics. 1998 Dec;102(6):1358-63. PubMed
• The Modified Atkins Diet for Children with Intractable Epilepsy

  Clinical References for The Modified Atkins Diet for Children with Intractable Epilepsy.

  • Sharma S, et al. Use of the modified Atkins diet in infantile spasms refractory to first-line treatment. Seizure. 2012 Jan;21(1):45-8. PubMed
  • Kim YM, et al. Various indications for a modified Atkins diet in intractable childhood epilepsy. Brain Dev. 2011 Oct 14. PubMed
  • Kossoff EH, et al. Prospective study of the Modified Atkins Diet in combination with a ketogenic liquid supplement during the initial month. J Child Neurol 2011;26(2):147-51. PubMed
  • Ito Y, et al. A modified Atkins diet is promising as a treatment for glucose transporter type 1 deficiency syndrome. Dev Med Child Neurol. 2011 Jul;53(7):658-63. PubMed
  • Miranda MJ, et al. Danish study of a Modified Atkins diet for medically intractable epilepsy in children: Can we achieve the same results as with the classical ketogenic diet? Seizure. 2011;20:151-155. PubMed
  • Kumada T, et al. Modified Atkins Diet for the Treatment of Nonconvulsive Status Epilepticus in Children. J Child Neurol. 2010;25(4):485-489. PubMed
  • Kossoff EH, at al. A pilot study of the modified Atkins diet for Sturge-Weber syndrome. Epilepsy Res. 2010 Dec;92(2-3):240-3. PubMed
  • Barzegar M, et al. A Modified Atkins Diet for Intractable Epilepsy. Iran J Child Neurology. 2010;4(3):15-20. Abstract
  • Tonekaboni SH, et al. Efficacy of the Atkins diet as therapy for intractable epilepsy in children. Archives of Iranian Medicine. 2010;13(6):492-7. PubMed
  • Porta N, et al. Comparison of seizure reduction and serum fatty acid levels after receiving the ketogenic and modified Atkins diet. Seizure. 2009;18(5):359–364. PubMed
  • Kang HC, et al. Use of a modified Atkins diet in intractable childhood epilepsy. Epilepsia. 2007;48(1):182–6. PubMed
  • Kossoff EH, et al. A randomized, crossover comparison of daily carbohydrate limits using the modified Atkins diet. Epilepsy Behav. 2007 May;10(3):432-6. PubMed
  • Kossoff EH, et al. A modified Atkins diet is effective for the treatment of intractable pediatric epilepsy. Epilepsia. 2006;47(2):421-4. PubMed
• Dietary Therapies for Adults with Epilepsy

  Clinical References for Dietary Therapies for Adults with Epilepsy

  • Wusthoff CJ, et al. The ketogenic diet in treatment of two adults with prolonged nonconvulsive status epilepticus. Epilepsia. 2010 Jun;51(6):1083-5. PubMed
• Infantile Spasms

  Clinical References for Infantile Spasms.

  • Sharma S, et al Use of the modified Atkins diet in infantile spasms refractory to first-line treatment. Seizure. 2012 Jan;21(1):45-8. PubMed
  • Numis AL, et al. The relationship of ketosis and growth to the efficacy of the ketogenic diet in infantile spasms. Epilepsy Res. 2011 Jun 21. PubMed
  • Hong AM, et al. Infantile spasms treated with the ketogenic diet: prospective single-center experience in 104 consecutive infants. Epilepsia. 2010 Aug;51(8):1403-7. PubMed
  • Kossoff EH, et al. A case-control evaluation of the ketogenic diet versus ACTH for new-onset infantile spasms. Epilepsia. 2008 Sep;49(9):1504-9. PubMed
  • Eun SH, et al. Ketogenic diet for treatment of infantile spasms. Brain Dev. 2006 Oct;28(9):566-71. PubMed
  • Kossoff EH, et al. Efficacy of the ketogenic diet for infantile spasms. Pediatrics. 2002 May;109(5):780-3. PubMed
• Glut1 Deficiency Syndrome

  Clinical References for Glut1 Deficiency Syndrome.

  • Ito Y, et al. A modified Atkins diet is promising as a treatment for glucose transporter type 1 deficiency syndrome. Dev Med Child Neurol. 2011 Jul;53(7):658-63. PubMed
  • Klepper J. Glucose transporter deficiency syndrome (GLUT1DS) and the ketogenic diet. Epilepsia. 2008 Nov;49 Suppl 8:46-9. PubMed
  • Cornejo VE, et al. Glucose transponer type 1 deficiency síndrome (GLUT-1 SD) treated with ketogenic diet. Report of one case. Rev Med Chil. 2007 May;135(5):631-5. PubMed
• Dravet Syndrome

  Clinical References for Dravet Syndrome

  • Nabbout R, et al. Ketogenic diet also benefits Dravet syndrome patients receiving stiripentol: A prospective pilot study. Epilepsia. 2011 Jul;52(7):e54-7. PubMed
  • Veggiotti P, et al. The ketogenic diet for Dravet syndrome and other epileptic encephalopathies: an Italian consensus. Epilepsia. 2011 Apr;52 Suppl 2:83-9. PubMed
  • Caraballo RH. Nonpharmacologic treatments of Dravet syndrome: focus on the ketogenic diet. Epilepsia. 2011 Apr;52 Suppl 2:79-82. PubMed
  • Caraballo RH, et al. Ketogenic diet in patients with Dravet syndrome. Epilepsia. 2005 Sep;46(9):1539-44. PubMed
• Myoclonic Astatic Epilepsy (also known as Doose Syndrome)

  Clinical References for Myoclonic Astatic Epilepsy (also known as Doose Syndrome).

  • Mulligan JE, et al. Myoclonic astatic epilepsy and the role of the ketogenic diet. Med Health R I. 2011 May;94(5):127-30. PubMed
  • Kossoff EH, et al. Will seizure control improve by switching from the modified Atkins diet to the traditional ketogenic diet? Epilepsia. 2010 Dec;51(12):2496-9. PubMed
  • Caraballo RH, et al. Ketogenic diet in patients with myoclonic-astatic epilepsy. Epileptic Disord. 2006 Jun;8(2):151-5. PubMed
• Sturge-Weber Syndrome

  Clinical References for Sturge-Weber Syndrome.

  • Kossoff EH, et al. A pilot study of the modified Atkins diet for Sturge-Weber syndrome. Epilepsy Res. 2010 Dec;92(2-3):240-3. PubMed
• Tuberous Sclerosis

  Clinical References for Tuberous Sclerosis.

  • Coppola G, et al.The effects of the ketogenic diet in refractory partial seizures with reference to tuberous sclerosis. Eur J Paediatr Neurol. 2006 May;10(3):148-51. Epub 2006 Apr 24. PubMed
  • Kossoff EH, et al. Tuberous sclerosis complex and the ketogenic diet. Epilepsia. 2005 Oct;46(10):1684-6. PubMed
• Pyruvate Dehydrogenase Deficiency

  Clinical References for Pyruvate Dehydrogenase Deficiency.

  • El-Gharbawy AH, et al. Follow-up of a child with pyruvate dehydrogenase deficiency on a less restrictive ketogenic diet. Mol Genet Metab. 2011 Feb;102(2):214-5. PubMed
  • Wexler ID, et al. Outcome of pyruvate dehydrogenase deficiency treated with ketogenic diets. Studies in patients with identical mutations. Neurology. 1997 Dec;49(6):1655-61. PubMed
  • Wijburg FA, et al. Leigh syndrome associated with a deficiency of the pyruvate dehydrogenase complex: results of treatment with a ketogenic diet. Neuropediatrics. 1992 Jun;23(3):147-52. PubMed
  • Falk RE, et al. Ketonic diet in the management of pyruvate dehydrogenase deficiency. Pediatrics. 1976 Nov;58(5):713-21. PubMed
• Refractory Status Epilepticus

  Clinical References for Refractory Status Epilepticus.

  • Cervenka MC, et al. The ketogenic diet for medically and surgically refractory status epilepticus in the neurocritical care unit. Neurocrit Care. 2011 Dec;15(3):519-24. PubMed
  • Nam SH, et al. The role of ketogenic diet in the treatment of refractory status epilepticus. Epilepsia. 2011 Nov;52(11):e181-4. PubMed
  • Wusthoff CJ, et al. The ketogenic diet in treatment of two adults with prolonged nonconvulsive status epilepticus. Epilepsia. 2010 Jun;51(6):1083-5. PubMed
  • Kumada T, et al. Modified Atkins diet for the treatment of nonconvulsive status epilepticus in children. J Child Neurol. 2010 Apr;25(4):485-9. PubMed
• Generalized vs. Focal Epilepsy

  Clinical References for Generalized vs. Focal Epilepsy.

  • Kayyali H, et al. A. The Ketogenic Diet Efficacy in Generalized vs Focal Epilepsy (abstract). In: American Epilepsy Society’s Annual Meeting; 2 Dec 2011-6 Dec-2011; Baltimore, MD. Abstract 2.293. Abstract
• Non Ketotic Hyperglycinemia

  Clinical References for Non Ketotic Hyperglycinemia.

  • Cusmai R, et al. Ketogenic diet in early myoclonic encephalopathy due to non ketotic hyperglycinemia. Eur J Paediatr Neurol. 2012 Jan 17. [Epub ahead of print] PubMed
• CDKL5 Mutation

  Clinical References for CDKL5 Mutation.

  • Moseley BD, et al. Historic, Clinical, and Prognostic Features of Epileptic Encephalopathies Caused by CDKL5 Mutations. Pediatr Neurol. 2012 Feb;46(2):101-5. PubMed